Biological mechanisms.
Reproducible measurement.

THEME 01

Skin biology and tissue repair

We study how epithelial tissues sense injury and coordinate repair, including the roles of mechanical cues, cellular state and interactions between skin cell populations. This work connects wound-healing mechanisms with broader questions about tissue integrity and fibrosis.

• Epithelial biology
• Wound healing
• Cellular state

THEME 02

Antimicrobial peptides and host defense

We investigate how epithelial cells produce and release antimicrobial peptides and how host-derived molecules contribute to protection against bacterial and viral challenges. The work links secretion mechanisms with the biological activity of innate defense molecules.

• Antimicrobial peptides
• Innate immunity
• Barrier tissues

THEME 03

Virology and host–pathogen interactions

We study viral infection and the cellular responses that influence it, including work involving dengue, SARS-CoV-2 and lumpy skin disease virus. Collaborative projects investigate antiviral activity and develop experimental approaches for assessing infection and neutralisation.

• Virology
• Host–pathogen interactions
• Antiviral research

THEME 04

Cellular health and circadian skin biology

We investigate how mitochondrial function, cellular stress and circadian regulation contribute to skin health. Collaborative studies examine relationships between cellular state, barrier function, tissue repair and biological responses to external molecules.

• Mitochondrial health
• Circadian biology
• Skin barrier

THEME 05

Biological reference standards and measurement

We develop and characterise biological reference materials and assays to support reproducible research and diagnostic measurement. The Reference Standard Project, a collaboration between NCBS and C-CAMP, includes work on virus-related reference materials and the comparability of measurements across laboratories.

• Reference materials
• Assay development
• Reproducibility